Rodrigue KAMGA WOUAMBO1*, MOUGNOL NWATSOCK A1, Serges TCHATCHOUANG2
1Estuary Academic and Strategic Institute, Higher Institute of Applied Health Sciences, University of Buea ; 2Départment of Biochemistry, University of Yaounde I
CaHReF 2018, Yaoundé Congres hall, 08 – 11 January 2019 , OSEP006
Background: Toxoplasmosis is a parasitic disease caused by toxoplasma gondii. Infections with toxoplasmosis usually cause no obvious symptoms in adults. In people with weak immune system like HIV infected patients, severe symptoms may occur such as cerebral toxoplasmosis. This study was conducted to evaluate the prevalence and risks factors of toxoplasmosis
Objectif: This study was conducted to evaluate the prevalence and risks factors of toxoplasmosis among people living with AIDS.
Methodolody: A cross-sectional study took place from January to March 2018 at Cité Verte District Hospital ‘in Yaounde, a semi-communal area in the Centre Region of Cameroon. Toxoplasma Immunocomb IgM and IgG antibodies were simultaneous done to each HIV positive participant. Data were analyzed with Epi info 4.0. Comparison of categorical variables was using X2 test and <0.05 was considered as statistically significant
Results: We enrolled 100 HIV+ subjects with mean age of 37.4(1.1 years old (21-66( comprising 66% women and 80 % HIV-1. The frequency of toxoplasmosis was 32% (32/100): it included 15% of IgM and 24% of IgG. We noticed 8% of probably acute infection (IgM+ IgG-), 7% of active infection (IgM+IgG+), 17% of probably chronic infection (IgM-IgG+) and 68% of negative (IgM-IgG-). Patients of the age group 34-45, were the most represented (37% (37/100)( and affected (32, 4% (12/37)(. Besides, the majority of HIV infected subjects got a cat (41.2% (21/51) vs. 22.4% (11/49), p=0.039(. Seventy eight percent of participants
Conclusion/Recommandation: The prevalence of toxoplasmosis was high in this study. The systematic screening of toxoplasmosis should be recommended to HIV positives patients. They should be informed about the risk factors of transmission of this disease.
Key Words: Toxoplasmosis, HIV infected patients, Risks factors.