Elvis DZELAMONYUY CHEM1
1Liverpool John Moores University,United Kingdom
CaHReF 2018, Yaoundé Congres hall, 08 – 11 January 2019 , OAEI001
Background: Inappropriate use of antibiotics is a global public health challenge and has been associated with antibiotic resistance. WHO reports show that efforts to promote rational antibiotic use in developing countries are poor.With the growing number of infections with antibiotic resistant bacteria, studies promoting rational drug use are highly necessary.
Objectif: we investigated prescribing patterns and predictors of antibiotic prescription in primary health care facilities to contribute data which could influence policy on antibiotic use.
Methodology: A cross sectional retrospective study was conducted from April 2014 to April 2015 in 26 randomly selected primary care facilities. Questionnaires were administered to 59 antibiotic prescribers to determine factors that predict antibiotic prescription. Data on antibiotic prescription was collected by review of consultation registers. The relationship between antibiotic prescription rate and demographic, prescriber and institution factors was analyzed using ANOVA. The best predictor of prescription was determined using multiple linear regression analysis.
Results: A total of 30,096 prescriptions were reviewed. Overall antibiotic prescription rate was 36.71%, with a mean of 1.14 antibiotics prescribed per patient. Amoxicillin was the most prescribed (29.9%). The most prevalent indications for prescription were respiratory tract infections (21.27%). All antibiotics prescribed were broad-spectrum. Antibiotics were prescribed for patients with malaria and also in situations where diagnosis was uncertain. Prescription by generic name was 98.36% while 99.87% was from Essential Drug List. Use of laboratory results, patient turnout and Performance Based Financing (PBF) significantly associated with antibiotic prescription rates (p Ë‚ 0.05). PBF moderated prescribing.
Conclusion/Recommandation: There was misuse of antibiotics in primary care facilities in study area. We recommend all primary care health facilities in study area to be included in the PBF scheme
Key Words: Antibiotic, Associated factors, Prescribing patterns, Prescription