The bacteriologic profile and drug resistance patterns of blood cultures isolated amongst patients attending the university teaching hospital yaounde.

CaHReF 2016, Yaoundé Conges hall, 23 – 26 August 2016 , PL143

Blood stream infections range from self-limiting infections to life threatening sepsis that require rapid and aggressive antimicrobial treatment. The prevalence of resistant blood borne isolates is increasing and also increasing mortality and long term hospital stay. As the practice of prescribing antibiotics is completely unregulated, cheap generics are available, usage of all kinds of antibiotics for even minor illnesses are widespread, and there are not many newer antimicrobials in research pipeline, it is foreseen that if the same kind of practice and scenario continues the antibiotic resistance is likely to go up and we will face serious crisis of antibiotics in near future. The main purpose of this study was to determine the blood bacteria profile and drug resistance pattern of blood cultures in the University Teaching Hospital from the 4th of May to the 5th of June 2016. A cross sectional hospital based study design was used and 128 participants were recruited for the study. Venous blood from these participants was inoculated and growth identified on Hemoline Diphasic Performance Medium. The antibiogram of the isolates was done on Mueller Hinton Agar using the disc diffusion technique. The following results were registered, 26 participants were positive for blood bacteria giving a 20.3% prevalence. These isolates were dominated by Gram positive cocci (Staphylococcus epidermidis (26.92%) and Staphyloccocus aureus (19.23%)) and Gram negative bacilli isolated include Klebsiella pneumonia (19.23%). The least isolated were the Yersinia spp and the Enterobacter species. Most of the Gram positive cocci isolates were found to be resistant to cotrimoxazole and tetracycline (53.3%) and more sensitive to tobarmycin and fusidic acid (80.0%). The Gram negative bacilli was found to be highly sensitive to levofloxacin, oxacillin and fosfomycin (63.6%) while they were also greatly resistant to cotrimoxazole and ciprofloxacin (81.8%).Thus making bacteriamia/septicaemia still remaining a major concern in this hospital.

Bactertiaemia, septicaemia, resistant patterns, University teaching hospital Yaounde